Strain Data Sheet

RBRC05559

Information1

Image
BRC No.RBRC05559
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tg(Crx-cre/ERT2)1Tfur
Former Common name129S6;B6C3-Tg(Crx-cre/ERT2)1Tfur, 129-CrxCreERT2, 129-CrxCreER Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Takahisa Furukawa, Osaka Bioscience Institute in 2008. The transgene was injected into the pronuclei of B6C3F1 fertilized eggs.
Strain descriptionCrx-creERT2 transgenic mice. This transgenic mouse expresses tamoxifen-inducible cre recombinase gene in retinal photoreceptor cells and progenitor cells under the control of the mouse Crx promoter.
Colony maintenanceCarrier x Noncarrier [C57BL/6NCrlCrlj]
ReferencesJ. Neurosci., 31, 16792-16807 (2011). 22090505

Health Report

Examination Date / Room / Racknull

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
ERT2estrogen receptor (ER), human ER with the triple mutation G400V/M543A/L544A)UNERT2

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
crePhage P1 Cre recombinaseUNcreCrx2K promoter

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
SV40 polyA signalUN

Information2

Donor DNAmouse Crx promoter, phage P1 Cre recombinase gene, SV40 polyA signal, human Estrogen receptor binding domain (ERT2)
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 31, 16792-16807 (2011).Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must contract an MTA with the DEPOSITOR (Osaka University).
DepositorTakahisa Furukawa (Osaka Bioscience Institute)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Mouse of the Month May 2013
Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data