RBRC05557

Information1

Image
BRC No.RBRC05557
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6J.MSM-Hiomt<MSM>
Former Common nameB6- Hiomt<MSM>
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Takaoki Kasahara, RIKEN Brain Science Institute and Shigeharu Wakana, RIKEN BioResource Center in 2011. This congenic strain was generated by backcrossing to C57BL/6J from MSM/Ms.
Strain descriptionC57BL/6J congenic strain having Hiomt gene derived from Japanese wild-derived inbred mice, MSM/Ms. Melatonin synthesis requires enzymes encoded by Aanat and Hiomt genes. B6J.MSM-Aanat<MSM> Hiomt<MSM> (RBRC05503), B6J.MSM-Aanat<MSM> (RBRC05556), B6J.MSM-Hiomt<MSM> (RBRC05557).
Colony maintenanceHomozygote x Homozygote
ReferencesProc. Natl. Acad. Sci. USA, 107, 6412-6417 (2010). 20308563

Health Report

Examination Date / Room / Rack2014/07/14Room:4-CRack:G
2014/05/19Room:4-CRack:G
2014/03/24Room:4-CRack:G
2014/01/20Room:4-CRack:G
2013/11/25Room:4-CRack:G
2013/09/24Room:4-CRack:G
2013/07/22Room:4-CRack:G
2013/05/20Room:4-CRack:G

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Asmtacetylserotonin O-methyltransferaseUNAsmt<MSM/Ms>MSM/Ms

Information2

Donor DNA
Research application
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEVELOPER (Dr. Takaoki Kasahara) using the Approval Form.
DepositorTadafumi Kato (RIKEN)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-
Lab HP

BRC mice in Publications

No Data