RBRC05542

Information1

Image
BRC No.RBRC05542
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Puf60<tm1>/CU
Former Common nameFIR floxed, B6-Puf60 floxed
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Kazuyuki Matsushita, Atsushi Iwama and Fumio Nomura, Graduate School of Medicine, Chiba University. C57BL/6 background (C57BL/6JJcl and C57BL/6NCrlCrlj mixed).
Strain descriptionFIR, RBP Interacting repressor (Puf60) floxed mice. A loxP site was inserted upstream of exon 3, and a PGK-neo cassette and loxP site were inserted down stream of exon 5. Conditional FIR deficient mice can be generated by crossing with tissue-specific Cre mice.
Colony maintenanceHeterozygote x Wild-type [C57BL/6NCrlCrlj]
ReferencesCancer Res., 66, 1409-1417 (2006). 16452196
Cancer Sci., 104, :149-156 (2013). 23113893
Oncotarget. 2014 Dec 31. [Epub ahead of print] 25671302
Mol. Cancer Res., ;11, 689-698 (2013). 23594796
Oncotarget, 4, Dec 21 2013.

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Puf60poly-U binding splicing factor 6015Puf60

Information2

Donor DNAMouse FBP Interacting repressor genomic DNA, Mouse PGK promoter, E. coli Neomycin resistance gene, Phage P1 loxP
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncotarget. 2014 Dec 31. [Epub ahead of print]In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested (will be announced).
DepositorFumio Nomura (Chiba University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data