BRC No.RBRC05535
SpeciesMus musculus
Strain nameC3H.C3B6-Tg(HTLV-I/LTR-pX)647Yiw
Former Common nameC3-HTLV-I/pX Tg#647
H-2 Haplotype
ES Cell line
Background strainC3H/HeNSlc
Strain developmentDeveloped by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 1991. Transgene was injected into the pronuclei of B6C3F1 fertilized eggs. C3H background.
Strain descriptionTransgenic mice having env-pX region of human T cell leukemia virus type-I (HTLV-I). About 40 % of Tg mice develop chronic arthritis resembling rheumatoid arthritis. C3H background.
Colony maintenanceCarrier x Noncarrier [or Crossing to C3H/HeNSlc]
ReferencesScience, 253, 1026-1028 (1991). 1887217

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
HTLV-Ihuman T cell leukemia virus type-IUNHTLV-I


Donor DNAhuman T cell leukemia virus type-I (HTLV-I) LTR, human T cell leukemia virus type-I (HTLV-I) env-pX region
Research applicationImmunology and Inflammation Research
Mouse Models for Human Disease
Specific Term and ConditionsPlease obtain the written consent from Professor Yoichiro Iwakura(iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science)for the use.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data