RBRC05512

Information1

Image
BRC No.RBRC05512
TypeInbred
SpeciesMus musculus
Strain nameC57BL/10ScCr
Former Common nameB10ScCr
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentMaintained by Gris Galanos, Max-Planck-Institute for Immunobiology
Strain descriptionThis strain is homozygous for the defective lipopolysaccharide and IL-12 interferon responses (Tlr4<lps-del> and Il12rb2<Ifnm-d>).
Colony maintenanceTlr4 : Homozygote x Homozygote ; Il12rb2 : Homozygote x Homozygote Homozygous mutant mice are viable and fertile.
ReferencesJ. Immunol., 167, 2106-2111 (2001). 11489994
Science, 282, 2085-2088 (1998). 9851930

Health Report

Examination Date / Room / Rack2020/02/17Room:3-ARack:E
2019/12/16Room:3-ARack:E
2019/10/21Room:3-ARack:E
2019/08/26Room:3-ARack:E
2019/08/26Room:3-ARack:E
2019/06/17Room:3-ARack:E
2019/06/17Room:3-ARack:E
2019/06/17Room:3-ARack:E

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Tlr4toll-like receptor 44Tlr4<lps-del>toll-like receptor 4; defective lipopolysaccharide

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Il12rb2interleukin 12 receptor, beta 26Il12rb2<Ifnm-d>interferon response to microorgansisms, defective

Information2

Donor DNA
Research application
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorHiroaki Takimoto (Kitasato University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
Strain AvailabilityCryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data