BRC No.RBRC05387
SpeciesMus musculus
Strain nameB6;B6C3(129)-Tg(NDE-hsp-Pkd2*D509V/Venus)1Hmd
Former Common nameB6-NDE-Pkd2m2-venus Tg#1
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Dr. Satoko Yoshiba and Dr. Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2010. The transgene was microinjected into the pronuclei of B6C3F1 fertilized eggs.
Strain descriptionThis transgenic mouse expresses the D509V variant Pkd2 and venus fusion gene on both sides of the node, node under the control of the mouse node-specific enhancer.
Colony maintenanceCarrier x Noncarrier [C57BL/6JJcl]
ReferencesScience, 338, 226-231 (2012). 22983710

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Pkd2polycystic kidney disease 2UNPkd2mouse Nodal node-notochord enhancer, mouse Hsp68 promoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
VenusGreen Fluorescent Protein, F46L (Jellyfish)UNVenus


Donor DNAMouse Pkd2 gene cDNA, SV40 polyA signal, Aequorea victoria Venus (改良型GFP), Mouse Nodal node-notochord enhancer, Mouse Hsp68 promoter
Research applicationFluorescent Proteins/lacZ System
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
DepositorHiroshi Hamada (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.

BRC mice in Publications

No Data