RBRC05377

Information1

Image
BRC No.RBRC05377
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC3H/HeN-Tg(CAG-CD4)17Yiw
Former Common nameC3H-CAG-CD4 Tg#17
H-2 Haplotype
ES Cell line
Background strainC3H/HeNSlc
Appearance
Strain developmentDeveloped by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2011. The transgene was microinjected into the pronuclei of C3H/HeNSlc fertilized eggs.
Strain descriptionHuman CD4 transgenic mice. These transgenic mice carry a human CD4 gene under the control of a chicken beta-actin promoter and cytomegalovirus enhancer. Two lines were deposited (RBRC05377 and RBRC05378).
Colony maintenanceCarrier x Wild-type [or Crossing to C3H/HeNSlc]
References

Health Report

Examination Date / Room / Rack2020/02/17Room:3-DRack:B
2019/12/16Room:3-DRack:B
2019/10/21Room:3-DRack:B
2019/08/26Room:3-DRack:B
2019/06/17Room:3-DRack:B
2019/04/15Room:3-DRack:B
2019/02/18Room:3-DRack:B
2018/12/17Room:3-DRack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
CD4CD4 antigenUNCD4CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)

Information2

Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), CD4 cDNA (human)
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. 後日指定(will be announced)Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data