Strain Data Sheet

RBRC05377

Strain Information

Image
BRC No.RBRC05377
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC3H/HeN-Tg(CAG-CD4)17Yiw
Former Common nameC3H-CAG-CD4 Tg#17
H-2 Haplotype
ES Cell line
Background strainC3H/HeNSlc
Appearance
Strain developmentDeveloped by Yoichiro Iwakura, The Institute of Medical Science, The University of Tokyo in 2011. The transgene was microinjected into the pronuclei of C3H/HeNSlc fertilized eggs.
Strain descriptionHuman CD4 transgenic mice. These transgenic mice carry a human CD4 gene under the control of a chicken beta-actin promoter and cytomegalovirus enhancer. Two lines were deposited (RBRC05377 and RBRC05378).
Colony maintenanceCarrier x Wild-type [or Crossing to C3H/HeNSlc]
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
CD4CD4 antigenUNCD4CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • obsolete no phenotypic analysis(MP:0003012)
    • Detailed phenotype data

    Ordering Information

    Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), CD4 cDNA (human)
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.) Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use.
    DepositorYoichiro Iwakura (The University of Tokyo)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. CAGGS MTA (English)
    4. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data