Strain Data Sheet
RBRC05282
Information1 | |
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| Image | |
| BRC No. | RBRC05282 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6.Cg-Cd300lb<tm1Toki>/Rbrc |
| Former Common name | LMIR5 (Acc. No. CDB0539K) |
| H-2 Haplotype | |
| ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
| Background strain | |
| Appearance | |
| Strain development | Developed by Toshio Kitamura, The Institute of Medical Science, The University of Tokyo. |
| Strain description | Cd300lb, CD300 antigen like family member B knockout mice. Homozygous mutant mice are protected from renal IRI (ischemia reperfusion injury) |
| Colony maintenance | Heterozygote x Wild-type [C57BL/6N] |
| References | J. Exp. Med., 207, 1501-1511 (2010). 20566714 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site11Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site11Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lacZbeta-galactosidase (E. coli)11 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter lox71mutant lox sequence11lox71 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP11loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)11neo; neomycin;mouse phosphoglycerate kinase promoter (PGK promoter) |
Information2 | |
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| Donor DNA | E. coli (Neo, LacZ), phage P1 (lox71, loxP), rabbit beta-globin 3' end, mouse phosphoglycerate kinase promoter (PGK promoter), mouse PGK3’end, yeast FRT (flipase recombination target) site, mouse Cd300lb genomic DNA |
| Research application | Cre/loxP system FLP/frt system Fluorescent Proteins/lacZ System |
| Specific Term and Conditions | (1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Toshio Kitamura, The University of Tokyo, E-mail: kitamura@ims.u-tokyo.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0539K and Web. Site (http://www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Exp Med. 2010 207(7):1501-11.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
| Depositor | RIKEN CDB (RIKEN CDB) |
| Strain Status |  Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
| Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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