RBRC05282

Information1

Image
BRC No.RBRC05282
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameLMIR5 (Acc. No. CDB0539K)
Former Common name
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Toshio Kitamura, The Institute of Medical Science, The University of Tokyo.
Strain descriptionCd300lb, CD300 antigen like family member B knockout mice. Homozygous mutant mice are protected from renal IRI (ischemia reperfusion injury)
Colony maintenanceHeterozygote x Wild-type [C57BL/6N]
ReferencesJ. Exp. Med., 207, 1501-1511 (2010). 20566714

Health Report

Examination Date / Room / Rack2014/09/17Room:3-CRack:A
2014/08/18Room:3-CRack:A
2014/06/27Room:3-CRack:A
2014/06/16Room:3-CRack:A
2014/04/21Room:3-CRack:A
2014/02/18Room:3-CRack:A
2013/12/16Room:3-CRack:A

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Cd300lbCD300 antigen like family member B11Cd300lb<tm1Toki>targeted mutation 1, Toshio Kitamura

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site11Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site11Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)11

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lox71mutant lox sequence11lox71

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP11loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)11mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAE. coli (Neo, LacZ), phage P1 (lox71, loxP), rabbit beta-globin 3' end, mouse phosphoglycerate kinase promoter (PGK promoter), mouse PGK3’end, yeast FRT (flipase recombination target) site, mouse Cd300lb genomic DNA
Research applicationCre/loxP system
FLP/frt system
Fluorescent Proteins/lacZ System
Specific Term and Conditions(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Toshio Kitamura, The University of Tokyo, E-mail: kitamura@ims.u-tokyo.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0539K and Web. Site (http://www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Exp Med. 2010 207(7):1501-11.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
DepositorRIKEN CDB (RIKEN CDB)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data