Strain Data Sheet

RBRC05279

Strain Information

Image
BRC No.RBRC05279
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Tg(Olfr16-Olr226*D126R/R127D,-Nrp1,-gapECFP)1Hsak/Rbrc
Former Common nameI7(RDY)-ires-Nrp1-ires-gap-ECFP:IANC (Acc. No.CDB0449T)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Hitoshi Sakano, Graduate School of Science, University of Tokyo.
Strain descriptionA mutant-type odorant receptor, I7 (D126R/R127D), Neuropilin-1, and an axonal marker gene, gap-ECFP, are expressed under MOR23 (Olfr16) gene promoter.
Colony maintenanceCarrier x Noncarrier [C57BL/6N]
References
Pre-target axon sorting establishes the neural map topography.
Imai T, Yamazaki T, Kobayakawa R, Kobayakawa K, Abe T, Suzuki M, Sakano H
Science,325, 585-590 (2009). 19589963

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
ECFP Enhanced Cyan Fluorescent Protein (Aequorea victoria)UNECFP
Gap43
MGI:95639		growth associated protein 43UNGap43
Ires internal ribosomal entry site (EMCV)UN
Nrp1 neuropilin 1UNNrp1

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • normal phenotype (MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAI7 (RDY) (rat), Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires), ECFP cDNA (Aequorea aequorea), Neuropilin-1, mouse gap43 palmitoylation signal
    Research applicationCell Biology Research
    Fluorescent Proteins/lacZ System
    covid19_infection
    Specific Term and Conditions(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Hitoshi Sakano, The University of Tokyo, E-mail: sakano@mail.ecc.u-tokyo.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0449T and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Science. 2009 325(5940):585-90.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
    DepositorRIKEN CDB (RIKEN CDB)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    BRC mice in Publications

    No Data