RBRC05278

Information1

Image
BRC No.RBRC05278
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain namemHB-EGF (Acc. No.CDB0447T)
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Masato Kasuga, Kobe University Graduate School of Medicine.
Strain descriptionmHB-EGF transgenic mice. This transgenic mouse expresses HB-EGF in skeletal muscle under the control of the mouse MCK promoter-enhancer. Tg mice were protected from obesity, hepatic steatosis and insulin resistance when maintained on a high-fat diet.
Colony maintenanceCarrier x Noncarrier [C57BL/6N]
ReferencesEndocrinology, 150, 2683-2691 (2009). 19264873

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
null

Information2

Donor DNAマウス (MCK promoter and enhancer), マウス (HB cDNA), SV40 (イントロン領域), 大腸菌 (CAT), mouse HB-EGF
Research application
Specific Term and Conditions(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Masato Kasuga, Kobe University, E-mail: kasuga@ri.imcj.go.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0447T and Web. Site (http://www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Endocrinology. 2009 150(6):2683-91.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
DepositorRIKEN CDB (RIKEN CDB)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data