Strain Data Sheet

RBRC05271

Strain Information

Image
BRC No.RBRC05271
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameICR-Tg(p16-luc)53Eiha/Rbrc
Former Common namep16-luc (Acc. No. CDB0416T-53)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Eiji Hara, The Cancer Institute, Japanese Foundation for Cancer Research.
Strain descriptionp16-luc transgenic mice. These mice have a human p16<lnk4a> gene locus tagged with firefly luciferase.
Colony maintenanceCarrier x Noncarrier [or Crossing to Crlj : CD1(ICR)]
References
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.
Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann D J, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E
J. Cell Biol., 186, 393-407 (2009). 19667129

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
luc luciferaseUNluc human CDKN2A promoter
neo neomycin resistance gene (E. coli)UN

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • normal phenotype (MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNAHuman CDKN2A (p16ink4) genomic DNA, Firefly luciferase cDNA, E. coli neo
    Research application
    Specific Term and Conditions(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Eiji Hara, The Cancer Institute of Japanese Foundation for Cancer Research, E-mail:eiji.hara@jfcr.or.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0416T-53 and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Cell Biol. 2009 186(3):393-407.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published.
    DepositorRIKEN CDB (RIKEN CDB)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data