Strain Information | |
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Image | |
BRC No. | RBRC05271 |
Type | Transgene![]() |
Species | Mus musculus |
Strain name | ICR-Tg(p16-luc)53Eiha/Rbrc |
Former Common name | p16-luc (Acc. No. CDB0416T-53) |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Eiji Hara, The Cancer Institute, Japanese Foundation for Cancer Research. |
Strain description | p16-luc transgenic mice. These mice have a human p16<lnk4a> gene locus tagged with firefly luciferase. |
Colony maintenance | Carrier x Noncarrier [or Crossing to Crlj : CD1(ICR)] |
References | Real-time in vivo imaging of p16Ink4a reveals cross talk with p53. Yamakoshi K, Takahashi A, Hirota F, Nakayama R, Ishimaru N, Kubo Y, Mann D J, Ohmura M, Hirao A, Saya H, Arase S, Hayashi Y, Nakao K, Matsumoto M, Ohtani N, Hara E J. Cell Biol., 186, 393-407 (2009). 19667129 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
luc | luciferase | UN | luc | human CDKN2A promoter | |||
neo | neomycin resistance gene (E. coli) | UN |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | Human CDKN2A (p16ink4) genomic DNA, Firefly luciferase cDNA, E. coli neo |
Research application | |
Specific Term and Conditions | (1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Eiji Hara, The Cancer Institute of Japanese Foundation for Cancer Research, E-mail:eiji.hara@jfcr.or.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0416T-53 and Web. Site (https://large.riken.jp/distribution/mutant-list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (J Cell Biol. 2009 186(3):393-407.) (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | ![]() ![]() |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |