Strain Data Sheet

RBRC05264

Strain Information

Image
BRC No.RBRC05264
TypeCongenic
SpeciesMus musculus
Strain nameB6.MSM-(D16Mit71-D16Mit106)/Hkv
Former Common nameB6-Mx
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Nobuya Sasaki and Takashi Agui, Graduate School of Veterinary Medicine, Hokkaido University in 2009. D16Mit71-D16Mit106 including Mx locus of MSM/Ms was backcrossed to C57BL/6J.
Strain descriptionMx B6 congenic strain. D16Mit71-D16Mit106 including Mx, myxovirus (influenza virus) resistance locus of MSM/Ms was backcrossed to C57BL/6J.
Colony maintenanceHomozygote x Homozygote
References
Generation of congenic mouse strains by introducing the virus-resistant genes, Mx1 and Oas1b, of feral mouse-derived inbred strain MSM/Ms into the common strain C57BL/6J.
Moritoh K, Yamauchi H, Asano A, Yoshii K, Kariwa H, Takashima I, Isoda N, Sakoda Y, Kida H, Sasaki N, Agui T
Jpn. J. Vet. Res., 57, 89-99 (2009). 19827744

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased susceptibility to viral infection(MP:0002410)
  • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
    DepositorTakashi Agui (Hokkaido University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Approval form (Japanese / English)
    2. Order form (Japanese / English)
    3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data