Strain Data Sheet


Strain Information

BRC No.RBRC05261
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameDW/J-Tpst2<grt>/Hkv
Former Common nameDW-grt
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Takeshi Yoshida, Mie University School of Medicine. Maintained by Takashi Agui, Graduate School of Veterinary Medicine, Hokkaido University.
Strain descriptionHypothyroid growth-retarded mouse derived from Snell’s dwarf mouse. Homozygous mutant mice show a delayed pubertal growth and hypothyroidism. Homozygous females are infertile and males show markedly-decreased fertility.
Colony maintenanceHeterozygote X Wild-type
ReferencesJ. Vet. Med. Sci., 70, 1043-1049 (2008). 18981659
Biomed. Res. 31, 207-211 (2010). 20622471
Mol. Endocrinol., 21, 1713-1721 (2007). 17456791

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Tpst2protein-tyrosine sulfotransferase 25Tpst2<grt>protein-tyrosine sulfotransferase 2; growth retarded

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
DepositorTakashi Agui (Hokkaido University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Approval form (Japanese / English)
  2. Order form (Japanese / English)
  3. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data