Strain Data Sheet

RBRC05254

Strain Information

Image
BRC No.RBRC05254
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Pou2f3<tm1Abek>
Former Common nameB6-Pou2f3 KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Ichiro Matsumoto, Monell Chemical Senses Center.
Strain descriptionPou2f3 knockout mice.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
References
Skn-1a (Pou2f3) specifies taste receptor cell lineage.
Matsumoto I, Ohmoto M, Narukawa M, Yoshihara Y, Abe K
Nat. Neurosci., 14, 685-687 (2011). 21572433

Health Report

Examination Date / Room / Rack2023/08/07Room:2-検Rack:C
2023/05/08Room:2-検Rack:C
2023/02/06Room:2-検Rack:C

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Pou2f3POU domain, class 2, transcription factor 39Pou2f3targeted mutation 1, Keiko Abe

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal bitter taste sensitivity(MP:0004210)

  • abnormal gustatory papilla taste bud morphology(MP:0006260)

  • abnormal liquid preference(MP:0001423)

  • abnormal sweet taste sensitivity(MP:0004209)

  • abnormal umami taste sensitivity(MP:0004213)
    • Detailed phenotype data

    Ordering Information

    Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli Neomycin resistance gene (gDNA), mouse Pou2f3 genomic DNA
    Research application
    Specific Term and ConditionsThe RECIPIENIT of BIOLOGICAL RESOURCE must notify the content of the research to the DEPOSITOR and obtain a prior written consent on use of it from the DEPOSITOR. (Ichiro Matsumoto: ichiro.matsumoto1@gmail.com). The RECIPIENT of BIOLOGICAL RESOURCE agrees to include the DEPOSITOR and its colleagues as co-authors in first publication of the results obtained by use of the B|OLOGICAL RESOURCE. In publishing the research results obtained by use of the BTOLOGICAL RESOURCE, a citation of the following literature designated by the DEPOSITOR is requested. Nat Neurosci.2011(6):685-7.
    DepositorIchiro Matsumoto (Monell Chemical Senses Center)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data