RBRC05197

Information1

Image
BRC No.RBRC05197
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129P2-Mll1<tm1Tok>
Former Common nameMll KO
H-2 Haplotype
ES Cell lineE14.1 [129P2/OlaHsd]
Background strain
Appearance
Strain developmentDeveloped by Hideshi Yagi and Toshihisa Komori, Osaka University Medical School in 1998.
Strain descriptionMll1 knockout mice. Homozygous mutant mice are embryonic lethal (E11) due to hematopoietic disorder. Heterozygous mice show somewhat poor growth compared to wild-type.
Colony maintenanceHeterozygote X Wild-type [C57BL/6J]
ReferencesBlood, 92, 108-117 (1998). 9639506

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Mll1myeloid/lymphoid or mixed-lineage leukemia 19Mll1<tm1Tok>targeted mutation 1, Toshihisa Komori

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)9mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAE. coli Neomycin resistance gene, Mouse Mll gene genome, Mouse phosphoglycerate kinase promoter, SV40 PolyA signal
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature designated by the DEPOSITOR is requested. Blood, 92, 108-117, 1998.  RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorMakoto Sato (University of Fukui)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data