Strain Data Sheet

RBRC05184

Strain Information

Image
BRC No.RBRC05184
TypeCongenic
SpeciesMus musculus
Strain nameA.SM-(D11Mit10-D11Mit48)
Former Common nameA.SM-Chr11H
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Tamio Ohno, Nagoya University Graduate School of Medicine. These congenic strains were produced by backcrossing of the following regions of SM/J onto the A/J.
Strain descriptionA/J congenic strains containing the region of chromosome 11 of SM/J. Regions of backcrossed: 11A (RBRC05510): D11Mit4-D11Mit279, 11B (RBRC05178): D11Mit106-D11Mit163, 11C (RBRC05179): D11Mit106-D11Mit140, 11D (RBRC05180): D11Mit140-D11Mit48, 11E (RBRC05181): D11Mit4-D11Mit48, 11F (RBRC05182): D11Nds1-D11Mit48, 11G (RBRC05183): D11Mit122-D11Mit48, 11H (RBRC05184): D11Mit10-D11Mit48, 11I (RBRC05706): D11Mit140-D11Mit8, 11J (RBRC06026): D11Mit106-D11Mit217, 11K(RBRC06027): D11Mit106-D11Mit173, 11L (RBRC06028): D11Mit236-D11Mit140.
Colony maintenanceHomozygote x Homozygote
References
Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11.
Maegawa T, Miyasaka Y, Kobayashi M, Babaya N, Ikegami H, Horio F, Takahashi M, Ohno T
Mamm. Genome, 29(3):273-280 (2018). 29523950

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased circulating insulin level(MP:0002727)

  • hyperglycemia(MP:0001559)

  • increased susceptibility to non-insulin-dependent diabetes(MP:0020087)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research applicationGenetics Research
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorTamio Ohno (Nagoya University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data