Strain Data Sheet



BRC No.RBRC05074
SpeciesMus musculus
Strain nameB6;B6D2-Tg(CAG-flag-H2A.Z)
Former Common nameB6-Flag/H2A.Z Tg
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Nashun Buhe, Masashi Yukawa and Fugaku Aoki, Graduate School of Frontier Sciences, The University of Tokyo in 2009. Transgene was injected into the pronuclei of B6D2F1 fertilized eggs.
Strain descriptionFlag-H2A.Z (H2afz) transgenic mice. H2A.Z gene is highly conserved across species and is essential for the viability of various organisms.
Colony maintenanceCarrier x Noncarrier
ReferencesDevelopment, 137, 3785-3794 (2010). 20943707
Structure, 16, 166-179 (2008). 18275809

Health Report

Examination Date / Room / Racknull


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
H2afzH2A histone family, member ZUNH2afzCAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)


Donor DNACAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA), Flag-tag cDNA, Mouse Histone H2A.Z (H2afz) gene cDNA
Research application
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorFugaku Aoki (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Mouse of the Month Oct 2011
Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. CAGGS MTA (English)
  4. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data