Strain Data Sheet

RBRC04939

Strain Information

Image
BRC No.RBRC04939
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6.B6D2-Tg(A1AT-Adam8)18
Former Common nameB6-A1AT-Adam8 Tg (CD156-Tg)
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Yasunori Higuchi, Oita University Faculty of Medicine in around 2000.
Strain description
Colony maintenanceCarrier x Noncarrier [C57BL/6NJcl]
References
Role of ADAM8 in experimental asthma.
Matsuno O, Miyazaki E, Nureki S, Ueno T, Kumamoto T, Higuchi Y
Immunol. Lett., 102, 67-73 (2006). 16154205

CD156 transgenic mice. Different responses between inflammatory types.
Higuchi Y, Yasui A, Matsuura K, Yamamoto S
Pathobiology, 70, 47-54 (2002). 12415192

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Adam8a disintegrin and metallopeptidase domain 8UNAdam8human alpha1 anti-trypsin inhibitor promoter, rabbit beta-globin polyA signal

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • lung inflammation(MP:0001861)
    • Detailed phenotype data

    Ordering Information

    Donor DNAMouse CD156 (膜外部) cDNA, human alpha1 anti-trypsin inhibitor promoter, rabbit beta-globin polyA signal, Rabbit beta-globin intron
    Research application
    Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
    DepositorYasunori Higuchi (Oita University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data