RBRC04906

Information1

Image
BRC No.RBRC04906
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameD1.129P2(Cg)-Cxcr4<tm1Yiw> Tg(Lck-cre)1Jtak
Former Common nameD1-Cxcr4 floxed/LckCre Tg
H-2 Haplotype
ES Cell lineE14.1 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain description
Colony maintenanceDBA/1JJmsSlc
ReferencesArthritis Res. Ther., 12, R188 (2010). 20939892

Health Report

Examination Date / Room / Rack2018/10/15Room:3-CRack:E
2018/08/20Room:3-CRack:E
2018/06/18Room:3-CRack:E
2018/04/16Room:3-CRack:E
2018/02/19Room:3-CRack:E
2017/12/18Room:3-CRack:E
2017/10/16Room:3-CRack:E
2017/08/21Room:3-CRack:E

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Cxcr4chemokine (C-X-C motif) receptor 41Cxcr4<tm1Yiw>targeted mutation 1, Yoichiro Iwakura

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP1loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP1loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)1mouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
crePhage P1 Cre recombinaseUNcremouse lck promoter

Information2

Donor DNAE. coli Neomycin resistance gene, mouse phosphoglycerate kinase promoter (PGK promoter), mouse Lck promoter, phage P1 Cre recombinase gene, phage P1 loxP sites, mouse Cxcr4 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Arthritis Res. Ther., 12, R188 (2010). Eur. J. Immunol., 28(7):2159-2166 (1998).Please obtain the written consent from Professor Yoichiro Iwakura (iwakura@rs.tus.ac.jp; Research Institute for Biological Sciences, Tokyo University of Science) for the use. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data