BRC No.RBRC04901
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6D2;129(Cg)-Sox2<tm2.1Knd>
Former Common nameSox2 enhancer N2 KO
H-2 Haplotype
ES Cell line
Background strainSlc:B6D2F1
Strain developmentDeveloped by Hisato Kondoh, Graduate School of Frontier Biosciences, Osaka University in 2007. An enhancer N2 was replaced with floxed neocassette. Cre-mediated recombination by corossing with CAGGS-Cre mice removed the neo cassete. The mice were crossed to B6D2F1.
Strain description
Colony maintenanceHomozygote x Heterozygote [or Crossing to Slc:B6D2F1] Homozygous mutant mice are viable and fertile.
ReferencesDev. Biol., 352, 354-366 (2011). 21185279

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Sox2SRY-box containing gene 23Sox2<tm2.1Knd>targeted mutation 2.1, Hisato Kondoh


Donor DNABacteriophage P1 Flox 配列
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Developmental Biology, 352, 354-366 (2011).
DepositorHisato Kondoh (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.

BRC mice in Publications

No Data