RBRC04892

Information1

Image
BRC No.RBRC04892
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6(Cg)-Aicda<tm2.1Hon>
Former Common nameB6-AID KI/G23S
H-2 Haplotype
ES Cell lineBruce 4 [B6.Cg-Thy1<a>]
Background strain
Appearance
Strain developmentDeveloped by Min Wei and Tasuku Honjo, Gradutate School of Medicine, Kyoto University in 2007.
Strain description
Colony maintenanceHeterozygote x Wild-type [C57BL/6J(Crlj)]
ReferencesNat. Immunol., 12, 264-270 (2011). 21258321
Nat. Immunol., 5, 707-712 (2004). 15195091

Health Report

Examination Date / Room / Rack2012/05/21Room:4-ARack:K
2012/03/26Room:4-ARack:K
2012/01/23Room:4-ARack:K

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Aicdaactivation-induced cytidine deaminase6Aicda<tm2.1Hon>targeted mutation 2, Tasuku Honjo

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP6loxP

Information2

Donor DNAPhage P1 loxP site, mouse Aicda (G23S) genomic DNA
Research applicationCre/loxP system
Specific Term and Conditions1) The RECIPIENT shall use the BIOLOGICAL RESOURCE only for academic research for the purpose of publishing the research results.
2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR and a citation of the following literature(s) designated by the DEPOSITOR are requested. Nat. Immunol., 12, 264-270 (2011).
3) RECIPIENT shall notify the PROVIDER upon filing a patent application claiming modification of the BIOLOGICAL RESOURCE or method(s) of manufacture or use(s) of the BIOLOGICAL RESOURCE.
DepositorTasuku Honjo (Kyoto University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Honjo Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

No Data