Strain Data Sheet

RBRC04883

Strain Information

Image
BRC No.RBRC04883
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Fcnb<tm1Tefu>
Former Common nameFcnB KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearance
Strain developmentDeveloped by Yuichi Endo, Fukushima Medical University in 2006. C57BL/6 background.
Strain description
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Fcnbficolin B2Fcnb targeted mutation 1, Teuzo Fujita
neoneomycin resistance gene (E. coli)2mouse phosphoglycerate kinase promoter (PGK promoter)

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • decreased susceptibility to bacterial infection(MP:0002411)

  • immune system phenotype(MP:0005387)

  • impaired lectin complement pathway(MP:0009062)

  • increased susceptibility to bacterial infection induced morbidity/mortality(MP:0009788)

  • increased susceptibility to bacterial infection(MP:0002412)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse Phosphoglycerate kinase promoter (PGK promoter), E. coli Neomycin resistance gene, mouse Fcnb genomic DNA
    Research application
    Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. If the RECIPIENT submit any results that are obtained from the BIOLOGICAL RESOURCE to research journals, the DEPOSITOR/DEVELOPER must be added as co-authors in the first publication. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
    DepositorTeizo Fujita (Fukushima Medical University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data