Strain Data Sheet


Strain Information

BRC No.RBRC04860
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB10.C-Tyr<c>/Hir
Former Common nameB10-c
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Tomohisa Hirobe, National Institute of Radiological Sciences in 1986. Albino (c) locus from BALB/cCrJms was backcrossed into the C57BL/10JMsHir, and then mantained by sister-brother mating.
Strain descriptionC57BL/10 congenic strain of albino locus from BALB/c strain. Albino (a/a B/B c/c D/D P/P E/E). No melanocyte in skin and eyes.
Colony maintenanceHomozygote x Homozygote
ReferencesPigment Cell Res., 18, 2-12 (2005). 15649147
Histol Histopathol., 10, 223-237 (1995). 7756740
Pigment Cell Res., 12, 147-163 (1992). 10385911
Pigment Cell Melanoma Res., 24(3):462-478 (2011). 21375698
Pigment Cell Res., 5, 1-11 (1992). 1631016

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter

Ordering Information

Donor DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Pigmnet Cell Melanoma Res., 24(3):462-478 (2011). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorTomohisa Hirobe (National Institute of Radiological Sciences (NIRS))
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

Hamanaka T, Nishizawa K, Sakasegawa Y, Oguma A, Teruya K, Kurahashi H, Hara H, Sakaguchi S, Doh-Ura K.
Melanin or a Melanin-Like Substance Interacts with the N-Terminal Portion of Prion Protein and Inhibits Abnormal Prion Protein Formation in Prion-Infected Cells.
J Virol 91(6) (2017) 28077650