Strain Data Sheet

RBRC04856

Strain Information

Image
BRC No.RBRC04856
TypeInbred
SpeciesMus musculus
Strain nameC3H/HeJmsHir
Former Common nameC3H/Hir
H-2 Haplotype
ES Cell line
Background strainC3H/HeJmsHir
Appearance
Strain developmentMaintained by Tomohisa Hirobe, National Institute of Radiological Sciences. Introduced into National Institute of Radiological Sciences at 1986 from Central Institute for Experimental Animals. Deposited to RIKEN BRC at F115.
Strain descriptionC3H inbred mice strain. Agouti (A/A B/B C/C D/D P/P E/E). Low number of melanocytes.
Colony maintenanceSibling x Sibling
References
Genetic and epigenetic control of the proliferation and differentiation of mouse epidermal melanocytes in culture.
T Hirobe, H Abe
Pigment Cell Res., 12, 147-163 (1992). 10385911

Control of melanocyte proliferation and differentiation in the mouse epidermis.
T Hirobe
Pigment Cell Res., 5, 1-11 (1992). 1631016

Structure and function of melanocytes: microscopic morphology and cell biology of mouse melanocytes in the epidermis and hair follicle.
T Hirobe
Histol Histopathol., 10, 223-237 (1995). 7756740

Role of keratinocyte-derived factors involved in regulating the proliferation and differentiation of mammalian epidermal melanocytes.
Tomohisa Hirobe
Pigment Cell Res., 18, 2-12 (2005). 15649147

How are proliferation and differentiation of melanocytes regulated?
Tomohisa Hirobe
Pigment Cell Melanoma Res., 24(3):462-478 (2011). 21375698

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal coat/hair pigmentation (MP:0002075)

  • abnormal hair follicle bulb morphology (MP:0010681)

  • abnormal melanocyte morphology (MP:0002877)

  • decreased melanocyte number (MP:0012023)
    • Detailed phenotype data

    Ordering Information

    Donor DNA
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Pigmnet Cell Melanoma Res., 24(3):462-478 (2011). In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
    DepositorTomohisa Hirobe (National Institute of Radiological Sciences (NIRS))
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

    BRC mice in Publications

    No Data