RBRC04849

Information1

Image
BRC No.RBRC04849
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.B6CB-Ptges2<tm1>
Former Common nameMembrane-associated prostaglandin E2 synthase-2 (mPGES2) KO
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearance
Strain developmentDeveloped by Kikuko Watanabe, University of East Asia Guraduate School of Integrated Science and Art Division of Medical and Life Science.
Strain description
Colony maintenanceHeterozygote x Wild-type [C57BL/6J(Crlj)] Homozygous mutant mice are viable and fertile.
ReferencesNat Immunol. 2013 Jun;14(6):554-63. 23624557
Biochem. Biophys. Res. Commun., 341, 132-138 (2006). 16414015

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ptges2prostaglandin E synthase 22Ptges2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Frtyeast FRT (flippase recombination target) site2Frt

Gene symbolGene nameChr.Allele symbolAllele namePromoter
IRESinternal ribosomal entry site (EMCV)2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP2loxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)2

Information2

Donor DNAmouse PGES2 genomic DNA, E. coli neomycin resistance gene, E. coli beta-galactosidase gene, mouse, En-2 gene splice acceptor, EMCV internal ribosomal entry site, SV40 PolyA signal, P1 Phage loxP, yeast FRT (flipase recombination target) site
Research applicationCre/loxP system
Fluorescent Proteins/lacZ System
Specific Term and ConditionsPrior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from use of the BIOLOGICAL RESOURCE.
DepositorMotonao Nakamura (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data