RBRC04841
Information1 | |
|---|---|
| Image | |
| BRC No. | RBRC04841 |
| Type | Targeted Mutation |
| Species | Mus musculus |
| Strain name | B6N.129P2-Bhlhe40<tm1Homy> |
| Former Common name | Dec1 KO |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | C57BL/6NCrlCrlj |
| Appearance | |
| Strain development | |
| Strain description | |
| Colony maintenance | |
| References | J. Immunol., 185, 7330-7339 (2010). 21057086 |
Health Report | |
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| Examination Date / Room / Rack | 2012/03/26Room:4-BRack:C 2012/01/23Room:4-BRack:C 2011/11/28Room:4-BRack:C 2011/09/26Room:4-BRack:C |
Gene | |
|---|---|
| Gene info | Gene symbolGene nameChr.Allele symbolAllele namePromoter Gene symbolGene nameChr.Allele symbolAllele namePromoter neoneomycin resistance gene (Streptomyces fradiase)6herpes simplex virus thymidine kinase promoter (HSV tk promoter) |
Information2 | |
|---|---|
| Donor DNA | herpes simplex virus thymidine kinase promoter (HSV tk promoter), Streptomyces fradiase neomycin phosphotransferase genomic DNA, mouse Bhlhe40 genomic DNA |
| Research application | |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
| Depositor | Hiroaki Honda (Tokyo Women's Medical University) |
| Strain Status |  Frozen embryos Frozen sperm |
| Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
| Additional Info. | Lab HP (Japanese) Genotyping protocol -PCR- |
BRC mice in Publications |
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Hu J, Mao Z, He S, Zhan Y, Ning R, Liu W, Yan B, Yang J. Icariin protects against glucocorticoid induced osteoporosis, increases the expression of the bone enhancer DEC1 and modulates the PI3K/Akt/GSK3 beta/beta-catenin integrated signaling pathway. Biochem. Pharmacol. 136 109-121(2017) 28408345 |