Strain Data Sheet

RBRC04816

Strain Information

Image
BRC No.RBRC04816
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameB6:B6D2-Tg(Th-PhiC31*)1Imayo
Former Common nameTh-PhiC31 Tg
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Itaru Imayoshi, Institute for Virus Research Kyoto University in 2010. The transgene was injected into the pronuclei of B6D2F1 fertilized eggs.
Strain descriptionThis strain expresses a PhiC31 recombinase under the control of the TH (tyrosine hydroxy lase) promoter.
Colony maintenanceCarrier X Noncarrier [C57BL/6J(Crlj)] Tg mice are viable and fertile.
References
In vivo evaluation of PhiC31 recombinase activity in transgenic mice.
Imayoshi I, Hirano K, Kitano S, Miyachi H, Kageyama R
Neurosci. Res., 73(2), 106-114 (2012). 22608021

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
PhiC31PhiC31 recombinaseUNPhiC31rat tyrosine hydroxylase (TH) promoter
  • TH-deficient dopa-responsive dystonia(MedGEN)

    • Phenotype

    Annotation by Mammalian phenotyhpe ontology
  • normal phenotype(MP:0002873)
    • Detailed phenotype data

    Ordering Information

    Donor DNArat TH promoter, Synthetic PhiC31o, SV40 PolyA signal
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neurosci. Res., 73(2), 106-114 (2012).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Itaru Imayoshi (E-mail: iimayosh@virus.kyoto-u.ac.jp). (No approval form (Form D) is necessary).
    DepositorItaru Imayoshi (Kyoto University)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)
    Itaru Imayoshi HP
    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data