Strain Data Sheet

RBRC04805

Strain Information

Image
BRC No.RBRC04805
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Sept8<tm1.1>
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Hauke B. Werner and Julia Patzig, Max-Planck-Institute of Experimental Medicine. Exon 2 of the Sept8 gene was deleted.
Strain descriptionSept8 knock-out mice. Septins are a family of GTPase proteins that are required for cytokinesis in most eukaryotes. Homozygous mutant mice show an impaired nervous system structure and function.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene
Frtyeast FRT (flippase recombination target) site11Frt
Sept8septin 811Sept8targeted mutation 1.1

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • nervous system phenotype(MP:0003631)
    • Detailed phenotype data

    Ordering Information

    Donor DNAmouse Sept8 genomic DNA, yeast FRT (flipase recombination target) sites
    Research applicationFLP/frt system
    Specific Term and ConditionsIn case the BIOLOGICAL RESOURCE is distributed by RIKEN BRC BEFORE its first Medline/PubMed-listed publication by the DEPOSITOR, the material (BIOLOGICAL RESOURCE) will be provided on a collaborative basis with authorship for Hauke B. Werner and Julia Patzig, unless agreed upon otherwise. In case the time point of distribution of the BIOLOGICAL RESOURCE by RIKEN BRC is AFTER the first publication by the DEPOSITOR, a citation of the following literature(s) designated by the DEPOSITOR is requested, (will be announced). In any case a material transfer agreement shall be obtained with the aim to specify the research field.
    DepositorHauke B. Werner (Max Planck Institute)
    Strain Statusan icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data