BRC No.RBRC04797
SpeciesMus musculus
Strain nameB6;B6C3(129)-Tg(NDE-hsp-Pkd2*D509V,lacZ)3Hmd
Former Common nameNDE-m2Pkd2-lacZ Tg#3
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Dr. Satoko Yoshiba and Dr. Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2008. Transgene was injected into the pronuclei of B6C3F1 fertilized eggs.
Strain descriptionThis transgenic mouse strain expresses the Asp509Val variant Pkd2 and lacZ on both node under the control of the mouse node-specific enhancer.
Colony maintenanceCarrier X Noncarrier [C57BL/6JJcl]
ReferencesScience, 338, 226-231 (2012). 22983710

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
IRESinternal ribosomal entry site (EMCV)UN

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Pdk2pyruvate dehydrogenase kinase, isoenzyme 2UNPdk2mouse node-specific enhancer, hsp promoter

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)UN


Donor DNAマウス由来Nodalのノードエンハンサー, Pkd2cDNA, hspプロモーター, E. coli由来 LacZ遺伝子, ウィルス由来 IRES配列
Research applicationFluorescent Proteins/lacZ System
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
DepositorHiroshi Hamada (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.

BRC mice in Publications

No Data