RBRC04757

Information1

Image
BRC No.RBRC04757
TypeChemically-induced Mutation
SpeciesMus musculus
Strain nameB6(D2)-Polg<Rgsc625>
Former Common nameM100625
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Dr. Shigeharu Wakana, RIKEN Genomic Sciences Center in 2005.
Strain descriptionThis strain has been developed in ENU-mutagenesis Project in RIKEN GSC. A point-mutation in exon24 of polg (polymerase gamma) locus has found in the genome of a G1(DBF1) mutagenized founder mice by the gene-driven screen.This strain has been maintained by the full-sib mating for 3 generations. And then we produced mice from the intercross between the hetero (Rgsc625/+) mice, and screen the mice for phenotypic comparisons among 3 genotypes (Rgsc625/Rgsc625, Rgsc625/+ and +/+).
Colony maintenanceHeterozygote x Wild-type
References

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Polgpolymerase (DNA directed), gamma7Polgpolymerase (DNA directed), gamma

Information2

Donor DNA
Research application
Specific Term and ConditionsThe RECIPIENT of for-profit institution must contact the DEPOSITOR separately.
The RECIPIENT of not for-profit institution must contact and discuss in good faith with the DEPOSITOR regarding inventorship, ownership, patent filing and licese fees and others, prior to filing a patent or make a contract with license fees with a third party for invention or products obtained from research results by using the BIOLOGICAL RESOURCES.
DepositorRIKEN GSC (RIKEN GSC)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Additional Info.

BRC mice in Publications

No Data