BRC No.RBRC04757
TypeChemically-induced Mutation
SpeciesMus musculus
Strain nameB6(D2)-Polg<Rgsc625>
Former Common nameM100625
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Dr. Shigeharu Wakana, RIKEN Genomic Sciences Center in 2005.
Strain descriptionThis strain has been developed in ENU-mutagenesis Project in RIKEN GSC. A point-mutation in exon24 of polg (polymerase gamma) locus has found in the genome of a G1(DBF1) mutagenized founder mice by the gene-driven screen.This strain has been maintained by the full-sib mating for 3 generations. And then we produced mice from the intercross between the hetero (Rgsc625/+) mice, and screen the mice for phenotypic comparisons among 3 genotypes (Rgsc625/Rgsc625, Rgsc625/+ and +/+).
Colony maintenanceHeterozygote x Wild-type

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Polgpolymerase (DNA directed), gamma7Polgpolymerase (DNA directed), gamma


Donor DNA
Research application
Specific Term and ConditionsThe RECIPIENT of for-profit institution must contact the DEPOSITOR separately.
The RECIPIENT of not for-profit institution must contact and discuss in good faith with the DEPOSITOR regarding inventorship, ownership, patent filing and licese fees and others, prior to filing a patent or make a contract with license fees with a third party for invention or products obtained from research results by using the BIOLOGICAL RESOURCES.
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Additional Info.

BRC mice in Publications

No Data