Strain Data Sheet

RBRC04754

Information1

Image
BRC No.RBRC04754
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129S4-Socs3<tm1Ayos>
Former Common nameSocs3 floxed
H-2 Haplotype
ES Cell lineJ1 [129S4/SvJae]
Background strain
Appearance
Strain developmentDeveloped by Akihiko Yoshimura, Medical Institute of Bioregulation, Kyushu University.
Strain descriptionScocs3 floxed mice. LoxP sites were inserted in intron 1 and in the 3’UTR of exon 2.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl] Homozygous mice are viable and fertile.
ReferencesNat. Immunol., 4, 551-556 (2003). 12754507

Health Report

Examination Date / Room / Rack2022/07/11Room:3-BRack:E

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Socs3suppressor of cytokine signaling 311Socs3<tm1Ayos>targeted mutation 1, Akihiko Yoshimura

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP11loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP11loxP

Information2

Donor DNAPhage P1 loxP sites, Mouse Socs3 genomic DNA
Research applicationCre/loxP system
Immunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Nat. Immunol., 4, 551-556 (2003).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorAkihiko Yoshimura (Keio University)
Strain Statusan icon for Live miceLive mice
an icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityCryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Live mouse (1 to 3 months)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data