RBRC04742

Information1

Image
BRC No.RBRC04742
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC.B6CB-Ltb4r2<tm1Tksh>
Former Common nameBALB-BLT2 KO
H-2 Haplotype
ES Cell line
Background strainBALB/cCrSlc
Appearance
Strain developmentDeveloped by Dr. Takao Shimizu, Faculty of Medicine, University of Tokyo in 2005. A lacZ-neo was inserted into the protein coding region of Ltb4r2 gene (Expression of lacZ was not detected). The mutant mice were backcrossed to BALB/c.
Strain description
Colony maintenance
ReferencesJ. Exp. Med., 205, 759-766 (2008). 18378794
J. Biol. Chem., 280, 24816-24823 (2005). 15866883
FASEB J., 24, 4678-4690 (2010). 20667973
J. Biol. Chem., 276, 12454-12459 (2001). 11278893

Health Report

Examination Date / Room / Rack2013/04/01Room:3-3Rack:B
2013/02/04Room:3-3Rack:B
2012/12/03Room:3-3Rack:B
2012/10/01Room:3-3Rack:B
2012/08/06Room:3-3Rack:B
2012/06/04Room:3-3Rack:B
2012/04/02Room:3-3Rack:B
2012/02/06Room:3-3Rack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ltb4r2leukotriene B4 receptor 214Ltb4r2

Information2

Donor DNAMouse Ltb4r2 genomic DNA, E.coli beta-galactosidase, Mouse phophoglycerate kinase promoter (PGK promoter), E.coli Neomycin resistance gene, Mouse polyA
Research applicationFluorescent Proteins/lacZ System
Immunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. FASEB J., 24(12):4678-90 (2010).RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorTakao Shimizu (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Additional Info.Genotyping protocol -PCR-
Lab HP (Japanese)

BRC mice in Publications

No Data