Strain Data Sheet


Strain Information

BRC No.RBRC04741
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.B6CB-Ltb4r2<tm1Tksh>
Former Common nameB6-BLT2 KO
H-2 Haplotype
ES Cell line
Background strain
Strain developmentDeveloped by Dr. Takao Shimizu, Faculty of Medicine, University of Tokyo in 2005. A lacZ-neo was inserted into the protein coding region of Ltb4r2 gene (Expression of lacZ was not detected). The mutant mice were backcrossed to C57BL/6.
Strain description
Colony maintenance
ReferencesJ. Biol. Chem., 276, 12454-12459 (2001). 11278893
FASEB J., 24, 4678-4690 (2010). 20667973
J. Biol. Chem., 280, 24816-24823 (2005). 15866883
J. Exp. Med., 205, 759-766 (2008). 18378794

Health Report

Examination Date / Room / Rack


Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ltb4r2leukotriene B4 receptor 214Ltb4r2

Ordering Information

Donor DNAMouse Ltb4r2 genomic DNA, E.coli beta-galactosidase, Mouse phophoglycerate kinase promoter (PGK promoter), E.coli Neomycin resistance gene, Mouse polyA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. FASEB J., 24(12):4678-90 (2010). RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorTakao Shimizu (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)
Lab HP (Japanese)
Genotyping protocol -PCR-

BRC mice in Publications

No Data