RBRC04739

Information1

Image
BRC No.RBRC04739
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.B6CB-Ltb4r1<tm1Tksh>
Former Common nameB6-BLT1 KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Dr. Takao Shimizu, Faculty of Medicine, University of Tokyo in 2005. A lacZ-neo was inserted into exon 2 of the Ltb4r1 gene (Expression of lacZ was not detected). The mutant mice were backcrossed to C57BL/6.
Strain description
Colony maintenance
ReferencesJ. Immunol., 175, 4217-4225 (2005). 16177061
Am. J. Pathol., 176, 2352-2366 (2010). 20304963
Nature, 387, 620-624 (1997). 9177352
Biochem. Biophys. Res. Commun., 394, 673-678 (2010). 20226760
Biochimie., 92, 682-691 (2010). 20004699
Proc. Natl. Acad. Sci. USA, 106, 21294-21299 (2009). 19965376

Health Report

Examination Date / Room / Rack2012/10/15Room:3-DRack:D
2012/08/27Room:3-DRack:D
2012/06/18Room:3-DRack:D
2012/04/16Room:3-DRack:D
2012/02/20Room:3-DRack:D
2011/12/12Room:3-DRack:D
2011/10/17Room:3-DRack:D
2011/08/29Room:3-DRack:D

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ltb4r1leukotriene B4 receptor 114Ltb4r1<tm1Tksh>targeted mutation 1, Takao Shimizu

Information2

Donor DNAMouse Ltb4r1 genomic DNA, E.coli beta-galactosidase, Mouse phophoglycerate kinase promoter (PGK promoter), E.coli Neomycin resistance gene, Mouse polyA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Immunol., 175, 4217-4225 (2005).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorTakao Shimizu (The University of Tokyo)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-
Lab HP (Japanese)

BRC mice in Publications

No Data