RBRC04709

Information1

Image
BRC No.RBRC04709
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameFVB.Cg-Atp2b2<tm1Ges>
Former Common name
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped Dr. Gary Shull, University of Cincinnati College of Medicine. Deposited by Dr. Thomas Knoepfel, RIKEN Brain Science Institute.
Strain descriptionPMCA2 knockout mouse. Deficient in the plasma membrane Ca2+ ATPase variant 2, PMCA2. Homozygous mutant mice are viable but show motor deficits, deficits in hearing and disturbance of the sense of balance.
Colony maintenanceHeterozygote x Wild-type
ReferencesJ. Biol. Chem., 273, 18693-18696 (1998). 9668038

Health Report

Examination Date / Room / Rack2013/06/17Room:3-ARack:I
2013/04/15Room:3-ARack:I
2013/02/18Room:3-ARack:I
2012/12/10Room:3-ARack:I
2012/10/15Room:3-ARack:I
2012/08/27Room:3-ARack:I
2012/06/18Room:3-ARack:I
2012/04/16Room:3-ARack:I

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Atp2b2ATPase, Ca++ transporting, plasma membrane 26Atp2b2

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)6mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAmouse PMCA2 genomic DNA, E. coli neomycin resistance gene, mouse phosphoglycerate kinase promoter (PGK promoter)
Research application
Specific Term and ConditionsNo specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
DepositorThomas Knöepfel (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Contact Information
Genotyping protocol -PCR-

BRC mice in Publications

No Data