RBRC04138

Information1

Image
BRC No.RBRC04138
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Ace3<tm1Osb>
Former Common nameACE3 KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain description
Colony maintenance
ReferencesPLoS One, 5, e10301 (2010). 20421979

Health Report

Examination Date / Room / Rack2011/10/17Room:3-CRack:K
2011/08/29Room:3-CRack:K
2011/06/20Room:3-CRack:K
2011/05/30Room:3-CRack:K
2011/04/18Room:3-CRack:K
2011/04/18Room:3-CRack:K
2011/03/23Room:3-CRack:K
2011/03/22Room:3-CRack:K

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ace3angiotensin I converting enzyme (peptidyl-dipeptidase A) 311Ace3<tm1Osb>targeted mutation 1, Research Institute for Microbial Diseases, Osaka University

Information2

Donor DNAmouse ace3 genomic DNA, E. coli neo, mouse phosphoglycerate kinase promoter (PGK promoter), phage P1 loxP, yeast FRT (flipase recombination target) sites
Research application
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS One, 5, e10301 (2010).RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University (http://www.uic.osaka-u.ac.jp/en/index.html). The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
DepositorMasaru Okabe (Osaka University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Lab HP
Genotyping protocol -PCR-

BRC mice in Publications

Yu CJ, Tang LL, Liang C, Chen X, Song SY, Ding XQ, Zhang KY, Song BL, Zhao D, Zhu XY, Li HL, Zhang ZR.
Angiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy.
J Am Heart Assoc 5(2) (2015) 26892527