Strain Data Sheet

RBRC03897

Strain Information

Image
BRC No.RBRC03897
TypeGene TrapCartagena
SpeciesMus musculus
Strain nameB6.129P2-Glg1<Gt(KST005)Byg>
Former Common nameCfr KO
H-2 Haplotype
ES Cell line
Background strainC57BL/6
Appearance
Strain developmentDeveloped by Yuichiro Miyaoka and Atsushi Miyajima, The University of Tokyo in 2006.
Strain description
Colony maintenance
References
A novel regulatory mechanism for Fgf18 signaling involving cysteine-rich FGF receptor (Cfr) and delta-like protein (Dlk).
Miyaoka Y, Tanaka M, Imamura T, Takada S, Miyajima A
Development, 137, 159-167 (2010). 20023171

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Phenotype annotation from literatures by Mammalian phenotype ontology
  • abnormal caudal vertebrae morphology (MP:0002759)

  • abnormal intervertebral disk morphology (MP:0004173)

  • abnormal maxillary shelf morphology (MP:0004538)

  • abnormal tail morphology (MP:0002111)

  • cleft palate (MP:0000111)
    • more 7 phenotypes
  • decreased body size (MP:0001265)

  • decreased body weight (MP:0001262)

  • decreased fetal size (MP:0004200)

  • decreased fetal weight (MP:0009431)

  • decreased survivor rate (MP:0008770)

  • meteorism (MP:0009247)

  • postnatal lethality, incomplete penetrance (MP:0011086)
    • Detailed phenotype data

    Ordering Information

    Donor DNAMouse Intron1 and exon2 of En2 gene genome DNA, E. coli Beta-galactosidase gene cDNA, E. coli Neomycin resistance gene cDNA, SV40 PolyA signal genome DNA, E. coli Ampicillin resistance gene
    Research application
    Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Development, 137, 159-167 (2010).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and the founders of BayGenomics, and must obtain a prior written consent from the DEPOSITOR and the founders of BayGenomics.
    DepositorAtsushi Miyajima (The University of Tokyo)
    Strain Statusan icon for Frozen embryosFrozen embryos
    an icon for Frozen spermFrozen sperm
    Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
    Cryopreserved sperm (within 1 month)
    Cryopreserved embryos (within 1 month)
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)
    Lab HP (Japanese)

    BRC mice in Publications

    Miyaoka Y, Tanaka M, Imamura T, Takada S, Miyajima A.
    A novel regulatory mechanism for Fgf18 signaling involving cysteine-rich FGF receptor (Cfr) and delta-like protein (Dlk).
    Development 137(1) 159-67(2010) 20023171