RBRC03712

Information1

Image
BRC No.RBRC03712
TypeGene TrapCartagena
SpeciesMus musculus
Strain nameB6;129P2-Dgcr8<Gt(XG058)Byg>
Former Common nameDGCR8KO/XG058
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain development
Strain descriptionDGCR8 is a key molecule of biogenesis of microRNA. DGCR8-/- mice are embryonic lethal and DGCR8-/+ mice look healthy but could be models of human 22q11.2 deletion syndrome including schizophrenia.
Colony maintenance
ReferencesNat. Genet., 40, 751-760 (2008). 18469815
Nat. Genet., 39, 380-385 (2007). 17259983

Health Report

Examination Date / Room / Rack2011/04/18Room:3-CRack:A
2011/02/21Room:3-CRack:A
2011/02/01Room:3-CRack:A
2011/01/31Room:3-CRack:A
2011/01/31Room:3-CRack:A
2010/12/13Room:3-CRack:A
2010/10/18Room:3-CRack:A
2010/08/23Room:3-CRack:A

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
null

Information2

Donor DNAE coli Neomycin resistance gene, E coli beta-galactosidase, mouse EN2 gene intron, mouse Splice acceptor of EN2 gene exon2
Research application
Specific Term and ConditionsThe RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. All data got with this BIOLOGICAL RESOURCE must be published as a joint result with the DEPOSITOR.
DepositorTakashi Iwamoto (Chubu University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Lab HP (Japanese)
Genotyping protocol -PCR-

BRC mice in Publications

No Data