|Former Common name||Arx P355L-1 KI (B6)|
|ES Cell line||CCE/EK.CCE [129S/SvEv-Gpi1<c>]|
|Strain development||Developed by Dr. Kunio Kitamura, Mistubishi Kagaku Insitute of Life Sciences.|
|Strain description||Arx P355L variant knock-in mice|
|Colony maintenance||Heterozygote x Wild-type [C57BL/6J]|
|References||Hum. Mol. Genet., 18, 3708-3724 (2009). 19605412|
|Examination Date / Room / Rack|
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
|Donor DNA||ARX genomic DNA (mouse), Neomycin resistance gene (E. coli), MC1 promoter (HSV-tk)、PolyA signal (SV40)|
|Specific Term and Conditions||The BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization.|
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution.
|Depositor||Kunio Kitamura (Mitsubishi Kasei Institute of Life Sciences)|
|Strain Status||Frozen embryos|
|Strain Availability||Recovered litters from cryopreserved embryos (2 to 4 months)|
Cryopreserved embryos (within 1 month)
|Additional Info.||Necessary documents for ordering:|
Genotyping protocol -PCR-
BRC mice in Publications
Xu S, Hayashi Y, Takagishi Y, Itoh M, Murata Y.
Aristaless-related homeobox plays a key role in hyperplasia of the pancreas islet α-like cells in mice deficient in proglucagon-derived peptides.
PLoS One 8(5) e64415(2013) 23671715