|Former Common name||Arx-2 KO|
|ES Cell line||E14TG2a [129P2/OlaHsd]|
|Strain development||Developed by Kunio Kitamura, Mitsubishi Kagaku Institute of Life Sciences. E14 ES cells were used to generate the mutant mice.|
|Strain description||Arx gene knockout mice. A lacZ-neo cassette was inserted into the exon 2 of Arx gene. Hemizygous (-/Y) mutant males die within 12 hrs after birth. Main line: Arx-6 KO (RBRC03438).|
|Colony maintenance||Heterozygote (female) x Wild-type (male)[C57BL/6JJcl]|
|Examination Date / Room / Rack||No Data|
Gene symbolGene nameChr.Allele symbolAllele namePromoter
|Donor DNA||ARX genomic DNA (mouse), beta-galactosidase (E. coli), Neomycin resistance gene (E. coli), herpes simplex virus thymidine kinase promoter (HSV tk promoter), SV40 PolyA signal, Encephalomyocarditis virus (EMCV) internal ribosomal entry site (ires)|
|Research application||Mouse Models for Human Disease|
|Specific Term and Conditions||The BIOLOGICAL RESOURCE shall be used only for academic research purposes by|
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
|Depositor||Kunio Kitamura (Mitsubishi Kasei Institute of Life Sciences)|
|Strain Status||Frozen sperm|
|Strain Availability||Recovery and QC required prior to distribution|
BRC mice in Publications