Strain Data Sheet

RBRC03342

Strain Information

Image
BRC No.RBRC03342
TypeGene TrapCartagena
SpeciesMus musculus
Strain namejmj C9 GT
Former Common name
H-2 Haplotype
ES Cell lineE14 [129P2/OlaHsd]
Background strain
Appearance
Strain development
Strain descriptionHomozygous mutant mice are embryonic lethal.
Colony maintenance
References
Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation.
Takeuchi T, Yamazaki Y, Katoh-Fukui Y, Tsuchiya R, Kondo S, Motoyama J, Higashinakagawa T
Genes Dev. 1995 9(10): 1211-22. 7758946

Health Report

Examination Date / Room / Rack

Gene

Gene SymbolGene NameChr.Allele SymbolAllele NameCommon NamesPromoterDiseases Related to This Gene

Phenotype

Annotation by Mammalian phenotyhpe ontology
  • abnormal definitive hematopoiesis(MP:0002123)

  • abnormal erythropoiesis(MP:0000245)

  • abnormal heart development(MP:0000267)

  • abnormal heart left ventricle morphology(MP:0003921)

  • abnormal liver morphology(MP:0000598)
    • more 32 phenotypes
  • abnormal liver physiology(MP:0000609)

  • abnormal megakaryocyte progenitor cell morphology(MP:0002413)

  • abnormal myocardial fiber morphology(MP:0000278)

  • abnormal myocardial trabeculae morphology(MP:0002189)

  • abnormal nervous system development(MP:0003861)

  • abnormal neural fold formation(MP:0004837)

  • abnormal neural plate morphology(MP:0005657)

  • abnormal neural tube closure(MP:0003720)

  • abnormal neural tube morphology(MP:0002151)

  • abnormal splenic cell ratio(MP:0008826)

  • abnormal thymus cell ratio(MP:0008827)

  • anemia(MP:0001577)

  • decreased embryo size(MP:0001698)

  • decreased fetal derived definitive erythrocyte cell number(MP:0011243)

  • decreased hepatocyte number(MP:0000606)

  • delayed neural tube closure(MP:0002621)

  • dilated liver sinusoidal space(MP:0000602)

  • distended pericardium(MP:0000292)

  • edema(MP:0001785)

  • embryonic lethality during organogenesis, complete penetrance(MP:0011098)

  • embryonic lethality during organogenesis, incomplete penetrance(MP:0011108)

  • fetal growth retardation(MP:0004201)

  • hemorrhage(MP:0001914)

  • hepatic necrosis(MP:0001654)

  • incomplete rostral neuropore closure(MP:0000928)

  • lethality throughout fetal growth and development, complete penetrance(MP:0011099)

  • lethality throughout fetal growth and development, incomplete penetrance(MP:0011109)

  • liver hypoplasia(MP:0000600)

  • nervous system phenotype(MP:0003631)

  • small liver(MP:0000601)

  • spleen hypoplasia(MP:0000694)

  • thymus hypoplasia(MP:0001823)
    • Detailed phenotype data

    Ordering Information

    Donor DNA(1) a splicing acceptor site of the mouse zinc-finger gene Zfp 40 , (2) E. coli lacZ gene, (3) E. coli neor gene, (4) internal ribosome entry site (IRES) derived from encephalomyocarditis virus , (5) oligo nucleotide representing the nuclear transporting
    Research application
    Specific Term and ConditionsThe BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization.
    The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL RESOURCE for purposes of other than academic research.
    In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi Chemical Corporation.
    The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical Corporation of RECIPIENT organization, RECIPIENT name, the specific research purpose and the date of distribution.
    DepositorTakashi Takeuchi (Mitsubishi Kasei Institute of Life Sciences)
    Strain Statusan icon for Frozen embryosFrozen embryos
    Strain AvailabilityRecovery and QC required prior to distribution
    Additional Info.Necessary documents for ordering:
    1. Order form (Japanese / English)
    2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
    3. Acceptance of responsibility for living modified organism (Japanese / English)

    Genotyping protocol -PCR-

    BRC mice in Publications

    No Data