RBRC03118

Information1

Image
BRC No.RBRC03118
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tcfcp2l1<tm1.1Sjt>
Former Common nameTcfcp211nu11
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Yoshifumi Yamaguchi and Shinji Takada, Okazaki Institute for Integrative Bioscience in 2005. CJ7 (129S1/Sv-Oca2<+> Tyr<+> Kitl<+>) ES cells derived. Floxed exon 2 was removed by crossing with CAG-cre mice. The mutant mice were backcrossed to C57BL/6J over 5 times.
Strain descriptionTcfcp2l1 gene knockout mice. Exon 2 of the Tcfcp2l1 gene was removed via cre mediated recombination. Homozygous mutant mice are postnatal lethal.
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJcl]
ReferencesDevelopment, 133, 4737-4748 (2006). 17079272

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Tcfcp211transcription factor CP2-like 11Tcfcp211<tm1.1Sjt>targeted mutation 1.1, Shinji Takada

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP1loxP

Information2

Donor DNAPhage P1 loxP, mouse Tcfcp2l1 genomic DNA
Research applicationCre/loxP system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Dev. Dyn., 233, 484-495 (2005). Development,133, 4737-4348 (2006).The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorShinji Takada (National Institute for Basic Biology)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data