RBRC03111

Information1

Image
BRC No.RBRC03111
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameC57BL/6J-Tg(mDrd1-YFP)680-1Koba
Former Common name
H-2 Haplotype
ES Cell line
Background strainC57BL/6JJcl
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Dr. Kazuto Kobayashi, Fukushima Medical University School of Medicine in 2009.
Strain descriptionThis transgenic mice express a yellow fluorescent protein under the control of the mouse Drd1a (dopamine receptor D1A gene promoter.
Colony maintenanceCarrier x Noncarrier [C57BL/6JJcl]
ReferencesNeuron, 89 (3) 550-565 (2016). 26804993

Health Report

Examination Date / Room / Rack2011/11/07Room:2-3Rack:C
2010/09/13Room:4-ARack:J
2010/07/12Room:4-ARack:J
2010/05/17Room:4-ARack:J
2010/03/15Room:4-ARack:J

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
YFPYellow Fluorescent Protein (Jellyfish)UNYFPmouse Drd1 promoter

Information2

Donor DNAmouse Drd1 genomic DNA, Jellyfish YFP cDNA, Phage P1 loxP site (derived from pBACe3.6 vector, BAC clone RP23-47M2)
Research applicationFluorescent Proteins/lacZ System
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neuron, 89 (3) 550-565 (2016).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. The RECIPIENT shall contact the DEPOSITOR (Dr. Kazuto Kobayasi, kazuto@fmu.ac.jp) about the use of the BIOLOGICAL RESOURCE in advance.
DepositorKazuto Kobayashi (Fukushima Medical University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-
GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC's MTA. Please also read Schedule B.
Lab HP (Japanese)

BRC mice in Publications

Nagatomo K, Suga S, Saitoh M, Kogawa M, Kobayashi K, Yamamoto Y, Yamada K.
Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse.
Front Neuroanat 11 3(2017) 28203148

Nagai T, Nakamuta S, Kuroda K, Nakauchi S, Nishioka T, Takano T, Zhang X, Tsuboi D, Funahashi Y, Nakano T, Yoshimoto J, Kobayashi K, Uchigashima M, Watanabe M, Miura M, Nishi A, Kobayashi K, Yamada K, Amano M, Kaibuchi K.
Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
Neuron 89(3) 550-65. (2016) 26804993

Bin Saifullah MA, Nagai T, Kuroda K, Wulaer B, Nabeshima T, Kaibuchi K, Yamada K.
Cell type-specific activation of mitogen-activated protein kinase in D1 receptor-expressing neurons of the nucleus accumbens potentiates stimulus-reward learning in mice.
Sci Rep 8(1) 14413.(2018) 30258218