RBRC02850

Information1

Image
BRC No.RBRC02850
TypeTransgeneCartagena
SpeciesMus musculus
Strain nameFVB/N-Tg(Alb-Ppp1r15a)14Dron
Former Common nameAlb::GC transgenic mouse Tg/Tg strain: FVB/N
H-2 Haplotype
ES Cell line
Background strainFVB/N
Appearancealbino [A/A B/B c/c D/D P/P]
Strain developmentDeveloped by Drs Seiichi Oyadomari and David Ron, New York University School of Medicine. FVB background.
Strain descriptionAlb::GC mice. This transgenic mice express a GADD34 C-terminal fragment (aa 292-590) from a liver-specific albumin promoter. Reduced glucose production in liver is observed.
Colony maintenanceCarrier x CarrierTg mice are viable and fertile.
ReferencesCell Metab., 7, 520-532 (2008). 18522833

Health Report

Examination Date / Room / Rack2010/06/21Room:3-DRack:L
2010/04/19Room:3-DRack:L
2010/02/22Room:3-DRack:L
2009/12/14Room:3-DRack:L
2009/10/19Room:3-DRack:L

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15AUNPpp1r15amouse Albumin enhancer/promoter fragment

Information2

Donor DNAmouse Albumin enhancer/promoter fragment, Hamster GADD34 C-terminal fragment (aa 292-590)
Research application
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cell Metab., 7, 520-532 (2008).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. DEPOSITOR hereby excludes any and all warranties, implied or express, including warranties of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE or of non-infringement of patents or other proprietary right. The sample of BIOLOGICAL RESOURCE is provided "as is". In no event shall DEPOSITOR be liable for direct, indirect, special, incidental or consequential damages in connection with the BIOLOGICAL RESOURCE. RECIPIENT and RIKEN BRC will indemnify and hold DEPOSITOR harmless from any claims or liability resulting from the use of the BIOLOGICAL RESOURCE by you. Prior to filing an application for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall acquire the consent form the DEPOSITOR for such application.
DepositorDavid Ron (New York University School of Medicine)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data