RBRC02686

Information1

Image
BRC No.RBRC02686
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Tnxb<tm1Kmat>
Former Common nameTnx-/-(F10), TNX-/- F10
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strainC57BL/6NCrSlc
Appearanceblack [a/a B/B C/C]
Strain developmentDeveloped by Dr. Kenichi Matsumoto, Hokkaido University in 2001. This strain was backcrossed to C57BL/6 over 10 times.
Strain descriptionTnxb, tenascin XB knock-out mice. This strain is useful to study the biological function of extracellular matrix tenascin-X in vivo. TNX-/- F10 line.
Colony maintenanceHeterozygote x Wild-type [C57BL/6CrSlc]
ReferencesGenes Cells, 6, 1101 (2001) 11737270
Genes Cells, 9, 737 (2004) 15298681
Exp. Cell Res., 297, 404 (2004) 15212943

Health Report

Examination Date / Room / Rack2010/02/22Room:3-CRack:J
2009/12/14Room:3-CRack:J
2009/10/19Room:3-CRack:J
2009/08/24Room:3-CRack:J
2009/06/22Room:3-CRack:J
2009/04/21Room:3-CRack:J
2009/04/20Room:3-CRack:J
2009/02/23Room:3-CRack:J

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Tnxbtenascin XB17Tnxb<tm1Kmat >targeted mutation 1, Ken-ichi Matsumoto

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)17mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAE.coli neo, mouse tenascin-X genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter)
Research applicationMouse Models for Human Disease
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells, 6, 1101-1111 (2001).The RECIPIENT must contact the DEPOSITOR in the case of application for any publications, patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.
DepositorKen-ichi Matsumoto (Hokkaido University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Lab HP (Japanese)
Genotyping protocol -PCR-

BRC mice in Publications

No Data