RBRC02685

Information1

Image
BRC No.RBRC02685
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6CBA-Tnxb<tm1Kmat>
Former Common nameTnx-/-(A1), TNX-/- A1
H-2 Haplotype
ES Cell lineTT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain
Appearanceagouti [A/A B/B C/C]
Strain developmentDeveloped by Dr. Kenichi Matsumoto, Hokkaido University in 2001. C57BL/6 and CBA mixed background.
Strain descriptionTnxb, tenascin XB knock-out mice. This strain is useful to study the biological function of extracellular matrix tenascin-X in vivo. TNX-/- A line.
Colony maintenanceHomozygote x Homozygote
ReferencesExp. Cell Res., 297, 404 (2004) 15212943
Genes Cells, 6, 1101 (2001) 11737270
Genes Cells, 9, 737 (2004) 15298681

Health Report

Examination Date / Room / Rack2012/11/26Room:4-BRack:B
2012/11/21Room:4-BRack:B
2012/11/19Room:4-BRack:B
2012/09/24Room:4-BRack:B
2012/07/23Room:4-BRack:B
2012/07/04Room:4-BRack:B
2012/05/21Room:4-BRack:B
2012/05/07Room:4-BRack:B

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Tnxbtenascin XB17Tnxb<tm1Kmat >targeted mutation 1, Ken-ichi Matsumoto

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)17mouse phosphoglycerate kinase promoter (PGK promoter)

Information2

Donor DNAE.coli neo, mouse tenascin-X genomic DNA, mouse phosphoglycerate kinase promoter (PGK promoter)
Research applicationMouse Models for Human Disease
Specific Term and ConditionsThe RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells, 6, 1101-1111 (2001).The RECIPIENT must contact the DEPOSITOR in the case of application for any publications, patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.
DepositorKen-ichi Matsumoto (Hokkaido University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved embryos (within 1 month)
Additional Info.Lab HP (Japanese)
Genotyping protocol -PCR-

BRC mice in Publications

No Data