BRC No.RBRC02633
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-Bace2<tm1.2>
Former Common nameC57BL/6 BACE2 KO mice (BACE2Delta)
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strainC57BL/6JJmsSlc
Strain developmentDeveloped by Shou Takashima and Yasuhiro Hashimoto, RIKEN Brain Science Institute in 2006.
Strain description
Colony maintenanceHeterozygote x Wild-type [C57BL/6JJmsSlc] Homozygous mutant mice are viable and fertile.

Health Report

Examination Date / Room / RackNo Data


Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Bace2beta-site APP-cleaving enzyme 216Bace2<tm1.2>targeted mutation 1.2, Yasuhiro Hashimoto

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxP16loxP


Donor DNAPhage P1 loxP site, mouse Bace2 genomic DNA
Research applicationCell Biology Research
Cre/loxP system
Specific Term and ConditionsIn publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from use of the BIOLOGICAL RESOURCE. For period of two (2) years after deposition by the DEPOSITOR to the REKEN BRC, the RESIPIENT agrees to include the DEPOSITOR/DEVELOPER (Yashuhiro Hashimoto, Shou Takashima, Satoshi Futakawa) as a co-authors.
DepositorYasuhiro Hashimoto (Fukushima Medical University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-

BRC mice in Publications

No Data