Strain Information | |
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Image | |
BRC No. | RBRC02595 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Diap1<tm1Sna>/SiaRbrc |
Former Common name | mDia1(loxP) (Acc. No. CDB0437K) |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | |
Strain description | |
Colony maintenance | |
References | Impaired T lymphocyte trafficking in mice deficient in an actin-nucleating protein, mDia1. Sakata D, Taniguchi H, Yasuda S, Adachi-Morishima A, Hamazaki Y, Nakayama R, Miki T, Minato N, Narumiya S J. Exp. Med., 204, 2031-2038 (2007). 17682067 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |||||||
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Gene Symbol | Gene Name | Chr. | Allele Symbol | Allele Name | Common Names | Promoter | Diseases Related to This Gene |
Diap1 | diaphanous homolog 1 (Drosophila) | 18 | Diap1 | targeted mutation 1, Shuh Narumiya | |||
Frt | yeast FRT (flippase recombination target) site | 18 | Frt | ||||
Frt | yeast FRT (flippase recombination target) site | 18 | Frt | ||||
loxP | phage P1 loxP | 18 | loxP | ||||
loxP | phage P1 loxP | 18 | loxP | ||||
neo | neomycin resistance gene (E. coli) | 18 | mouse phosphoglycerate kinase promoter (PGK promoter) |
Phenotype | |
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Annotation by Mammalian phenotyhpe ontology | |
Detailed phenotype data |
Ordering Information | |
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Donor DNA | mouse phosphoglycerate kinase promoter (PGK promoter), E. coli neo, mouse PGK 3’ end, Phage P1 loxP, yeast FRT (flipase recombination target) sites |
Research application | Immunology and Inflammation Research |
Specific Term and Conditions | (1) The RECIPIENT shall obtain a prior agreement from Dr. Shuh NARUMIIYA (snaru@mfour.med.kyoto-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0437K and the BIOLOGICAL RESOURCE is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested, J Exp Med. 2007 Sep 3; 204 (9): 2031-8. (4) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |