RBRC02523

Information1

Image
BRC No.RBRC02523
TypeTargeted Mutation CongenicCartagena
SpeciesMus musculus
Strain nameB6.Cg-Drd1a<tm1Mok> Drd2<tm1Mok> Drd1a<tm1(tTA)Mok> Tg(TRE-Drd1a/lacZ)1Mok
Former Common nameD1R, TET, D1R, D2R KO, B6-D1R/D2R KO D1R/tTA TRE-D1R/lacZ
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionD1R (Drd1a) knockout, D2R (Drd2) knockout, D1R-tTA knock-in and TRE-D1R/lacZ transgene multiple mutant mice.
Colony maintenance
ReferencesFront Cell Dev Biol., 3:38 (2015). 26137459
Genes Cells. 1(2):253-68 (1996). 9140068
Cerebral Cortex., 25(12):4885-97 (2015). 26443442
Front Integr Neurosci., 8:56 (2014). 25076876
J. Neurosci., 28(50):13390-13400 (2008). 19074012

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Drd1dopamine receptor D113Drd1<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
tTAtTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain)13tTA

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Drd2dopamine receptor D29Drd2<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Drd1dopamine receptor D1AUNDrd1E. coli TRE promoter (tetracycline responsive promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
lacZbeta-galactosidase (E. coli)UN

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)UN

Information2

Donor DNADopamine receptor1, E. coli neo, xanthine phosphoribosyltransferase (Ecogpt)tTA (E. coli tet repressor (TetR), herpes simplex virus (HSV) VP16 activation domain), E. coli tetracycline operator, E. coli lacZ
Research applicationFluorescent Proteins/lacZ System
Tet system
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. J. Neurosci., 28, 13390-13400 (2008). Genes Cells, 1, 253-268 (1996).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data