RBRC02485

Information1

Image
BRC No.RBRC02485
TypeTargeted Mutation and TransgeneCartagena
SpeciesMus musculus
Strain nameB6.Cg-Hras1<tm1Mok> Nras<tm1Mok> Kras<tm1Mok> Tg(HRAS/floxed)1Mok
Former Common nameH-ras, N-ras, K-ras triple KO, L-Tg, B6-Hras KO/Nras KO/Kras KO/HRASfloxed Tg
H-2 Haplotype
ES Cell lineCCE/EK.CCE [129S/SvEv-Gpi1<c>]
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionHras knockout, Nras knockout, Kras knockout and Lras transgenic multiple mutant mice.
Colony maintenance
ReferencesOncogene, 15, 1151-1159 (1997). 9294608
Oncogene, 19, 2951-2956 (2000). 10871846
EMBO J. 21(5):1021-30 (2002). 11867530

Health Report

Examination Date / Room / RackNo Data

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele namePromoter
Csde1cold shock domain containing E1, RNA binding3Csde1

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Nrasneuroblastoma ras oncogene3Nras<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)3herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele namePromoter
Krasv-Ki-ras2 Kirsten rat sarcome viral oncogene homolog6Kras<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
HrasHarvey rat sarcoma virus oncogene7Hras<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele namePromoter
neoneomycin resistance gene (E. coli)7

Gene symbolGene nameChr.Allele symbolAllele namePromoter
HRASHarvey rat sarcoma virus oncogene (human)UNHRAS

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxPUNloxP

Gene symbolGene nameChr.Allele symbolAllele namePromoter
loxPphage P1 loxPUNloxP

Information2

Donor DNAE. coli neo, mouse N-ras genomic DNA, mouse H-ras genomic DNA, mouse K-ras genomic DNA, human H-ras genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 19, 2951-2956 (2000). EMBO J., 21, 1021-1030 (2000). Oncogene, 15, 1151-1159 (1997).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.

BRC mice in Publications

No Data